Abstract

Whenever imaging a diffusive medium using non-contact measurements in reflection mode, accounting for the diffuse/non-diffuse interface is of great relevance. In this talk we will show that the physical measurements of light emerging from a diffusive medium may be used directly to solve the inverse problem, producing more accurate results due to the fact that the actual surface profile is used. Additional speed improvements may be implemented by removing the effect of the boundary, rendering the medium infinite. Tips on how to obtain accurate results in a fast and robust manner will be shown, together with specific in-vivo imaging applications in small animals.

© 2016 Optical Society of America