Detecting Alterations in Cell Nanoarchitecture with Optical Imaging: Implications for Cancer Detection

Vadim Backman; Hariharan Subramanian; Prabhakar Pradhan; Yang Liu; Ilker Capoglu; Jeremy Rogers

doi:10.1364/LS.2008.LThD3

Frontiers in Optics 2008/Laser Science XXIV/Plasmonics and Metamaterials/Optical Fabrication and Testing
OSA Technical Digest (CD) (Optica Publishing Group, 2008),
paper LThD3
•https://doi.org/10.1364/LS.2008.LThD3

Detecting Alterations in Cell Nanoarchitecture with Optical Imaging: Implications for Cancer Detection

Vadim Backman, Hariharan Subramanian, Prabhakar Pradhan, Yang Liu, Ilker Capoglu, and Jeremy Rogers

Laser Science 2008

Rochester, New York United States
19–23 October 2008
ISBN: 978-1-55752-861-2

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Cellular Imaging Techniques (LThD)

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V. Backman, H. Subramanian, P. Pradhan, Y. Liu, I. Capoglu, and J. Rogers, "Detecting Alterations in Cell Nanoarchitecture with Optical Imaging: Implications for Cancer Detection," in Frontiers in Optics 2008/Laser Science XXIV/Plasmonics and Metamaterials/Optical Fabrication and Testing, OSA Technical Digest (CD) (Optica Publishing Group, 2008), paper LThD3.

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Abstract

We report a spectroscopic microscopy technique that, coupled with mesoscopic theory analysis, measures cellular nanoarchitecture otherwise undetectable by conventional microscopy. Human studies demonstrated that this technique can detect the earliest cellular alterations in carcinogenesis.

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