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High-resolution spectral-domain optical coherence microscopy at 1700 nm spectral band

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Abstract

Optical coherence microscopy (OCM) is a non-destructive 3-dimentional (3D) imaging technique with micrometer-scale resolution, which is based on optical coherence tomography (OCT) and confocal microscopy [1-3]. Recently, it has been demonstrated that the OCT imaging depth is improved by using 1700 nm spectral band, so called “optical window 3”, due to the lower light absorption and a local minimum of water absorption in the wavelength region [4-8]. In our group, we developed a supercontinuum (SC) laser source at the 1700-nm wavelength region and demonstrated that 1700-nm OCT allows us to visualize the structures of mouse brain at a depth up to 1.7 mm [9-11]. We also successfully demonstrated 3D highresolution visualization of myelinated axons in a mouse brain with 1700-nm OCM, which we developed based on a time-domain low-coherence interferometer [12]. In this presentation, we report high-resolution spectral-domain OCM (SD-OCM) at the 1700-nm spectral band for improving the imaging acquisition speed of 1700-nm OCM.

© 2017 Japan Society of Applied Physics, Optical Society of America

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