Abstract

Spectral imaging has great advantages in fluorescence assisted diagnosis and treatment of tumors. Autofluorescence interference often reduces image contrast in imaging with fluorophores that specifically accumulates into tumor tissues. Furthermore, the multi-color fluorescent-image guided surgery is recently attracting attention. Therefore, flexible wavelength separation techniques are required. However, developing of flexible endoscopic systems having a spectroscopic function is challenging because endoscopic systems which combines integrated tunable filters, such as LCTF or AOTF, on the distal image sensor increase the size of tip and reduce brightness and use of image transfer fiber bundles decreases spatial resolution. In this research we propose an endoscopic system based on compressive sensing technique ^[1] to capture fluorescence spectral image without sacrificing brightness, size, and resolution.

© 2017 Japan Society of Applied Physics, Optical Society of America