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  • International Quantum Electronics Conference
  • OSA Technical Digest (Optica Publishing Group, 1984),
  • paper MAA5

Protein–Protein Intermolecular Singlet Energy Transfer: The Use of Picosecond Spectroscopy for the Analysis of Light-Induced Protein Motions of Retinal Rod Cells

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Abstract

Picosecond spectroscopic techniques and photoreceptor proteins are utilized to ascertain the role of rapid molecular motions involved in the biochemistry of vision. The availability of five highly purified, functionally interacting photoreceptor proteins in our laboratory provided an opportunity to study the nature of protein-protein interactions involved in a multiprotein reaction cascade. Because the cascade of reactions observed are initiated by the pulsed bleaching of the visual pigment rhodopsin, we can (by suitable fluorescent labeling of the components) detect the signal (light)-initiated onset of putative rapid molecular vibrations and molecular movement involved in protein-protein communication.

© 1984 Optical Society of America

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