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Quantifying Tissue Stiffness and the Effect of Nonlinearity using Compression Optical Coherence Elastography

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Abstract

We demonstrate the modification of optical coherence elastography to advance from relative strain images to quantified tissue stiffness on the micro-scale. We highlight the nonlinear dependence of tissue stiffness on the applied load and consider how nonlinearity may help characterise soft tissues.

© 2015 Optical Society of America

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