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High-resolution and Wide Field-of-view Fourier Ptychographic Microscopy

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Abstract

I will report on a new computational method for microscopy, Fourier Ptychographic Microscopy. This method performs phase retrieval through illumination angle diversity and allows us to transform a standard microscope with a 0.08 NA objective into a high-performance gigapixel microscope with 0.8 micron resolution, field-of-view of 120 mm2 and a long depth-of-field of 0.3 mm. This method transform the general challenge of standard microscopy from one coupled to the physical limitations of the system’s optics to one that is computationally solvable. The method can significantly simplify digital pathology procedures.

© 2013 Optical Society of America

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