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  • 2019 Conference on Lasers and Electro-Optics Europe and European Quantum Electronics Conference
  • OSA Technical Digest (Optica Publishing Group, 2019),
  • paper eg_6_6

Graphene Near-field Interactions for the Observation of DNA Hybridization in Aqueous Environment with Nanoscale Resolution

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Abstract

We demonstrate that near field effects of graphene can be used to measure axial distances optically, well below the diffraction limit, with resolution down to 1 nm. First we fabricate a control sample using Plasma Enhanced – Chemical Vapour Deposition (PE-CVD) to deposit thin layers of SiO2 with known thicknesses on top of a CVD grown graphene sheet, and onto which a 2 nm thin Atto488-doped Poly Vinyl Alcohol (PVA) layer is spin-coated (Fig. 1A). The fluorescence lifetime values scale with the nanoscale distance from graphene, matching a theoretical description published recently by Gaudreau et al.1 (Fig. 1B). We use the established and tested fluorescence lifetime-to-nanoscale distance conversion to develop a genosensor.

© 2019 IEEE

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