Simultaneous Diffuse Optical and Bioluminescence Tomography to Improve Source Localization

Alexander Bentley; Alexander Bentley; Xiangkun Xu; Zijian Deng; Jonathan E. Rowe; Ken Kang-Hsin Wang; Hamid Dehghani; Hamid Dehghani

doi:10.1364/ECBO.2021.EM3C.6

European Conferences on Biomedical Optics 2021 (ECBO)
OSA Technical Digest (Optica Publishing Group, 2021),
paper EM3C.6
•https://doi.org/10.1364/ECBO.2021.EM3C.6

Simultaneous Diffuse Optical and Bioluminescence Tomography to Improve Source Localization

Alexander Bentley, Xiangkun Xu, Zijian Deng, Jonathan E. Rowe, Ken Kang-Hsin Wang, and Hamid Dehghani

European Conference on Biomedical Optics 2021

Munich Germany
20–24 June 2021
ISBN: 978-1-943580-95-8

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Theory, Algorithms, and Computational Tools II (EM3C)

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A. Bentley, X. Xu, Z. Deng, J. E. Rowe, K. K. Wang, and H. Dehghani, "Simultaneous Diffuse Optical and Bioluminescence Tomography to Improve Source Localization," in European Conferences on Biomedical Optics 2021 (ECBO), OSA Technical Digest (Optica Publishing Group, 2021), paper EM3C.6.

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Abstract

A novel algorithm to simultaneously recover bioluminescence source location and optical parameters is developed. In-vivo studies show 30% improvement in localization error while also providing local total hemoglobin concentration.

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