Abstract
Pulse oximeter has been a widely used instrument in hospitals or household for measuring arterial oxygen saturation value. Its annual global market value has exceeded USD 1 billion and is still growing. There are two main shortcomings in most pulse oximeters on the market: 1. database based algorithm limits the range of precision, and 2. incapable of measuring tissue oxygen saturation related to local tissue oxygen exchange condition. We developed a 3-wavelength frequency multiplexed intensity modulated diffuse reflectance system in which the modulation frequencies of the 3 light sources are different so that the light reflectance at the 3 wavelengths can be collected by the detector simultaneously. This allows us achieving determination of absorption and reduced scattering coefficients at the 3 wavelengths of the exactly same instant of time and this can lead to accurate quantification of tissue and arterial oxygen saturations. This technique works in conjunction with a photon diffusion equation and does not need to build a database in advance to calculate arterial oxygen saturation. In addition, capability of this system in measuring tissue oxygen saturation would facilitate swift monitoring of local tissue blood circulation.
© 2019 SPIE/OSA
PDF ArticleMore Like This
Lorenzo Spinelli, Davide Contini, Antonio Pifferi, Alessandro Torricelli, Udo M. Weigel, Helene Isler, Daniel Ostojic, Heidrun Wabnitz, and Martin Wolf
11074_48 European Conference on Biomedical Optics (ECBO) 2019
Xiaoman Xing, Emile R Mohler, Turgut Duduran, Chao Zhou, Gwen Lech, Arjun Yodh, and Guoqiang Yu
BSuE56 Biomedical Optics (BIOMED) 2008
Zhe Li, Jinchao Feng, Zhonghua Sun, Pengyu Liu, and Kebin Jia
SM4E.3 Optical Sensors (Sensors) 2020