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Conferences > ECBO > 2019 > CHNAI > 11074_14

Non-invasive optical assessment of intracranial pressure: pilot results in human patients

Wesley B. Baker, Tracy M. Flanders, Ramani Balu, Lian He, Kristina Heye, Elizabeth Mahanna Gabrielli, John J. Flibotte, Daniel J. Licht, Gregory G. Heuer, Arjun G. Yodh, and W. Andrew Kofke

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Abstract

We present pilot results on the validation of non-invasive assessment of elevated intracranial pressure with optical measurement of critical closing pressure. A strong correlation (r=0.85) between optical measurements of critical closing pressure and invasive measurements of intracranial pressure was observed in 5 infants with hydrocephalus, and 1 adult patient with diffuse hypoxic ischemic brain injury. By facilitating timely detection of intracranial hypertension, this approach has potential to reduce risk of brain damage in hydrocephalus and other vulnerable patient populations.

© 2019 SPIE/OSA

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