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Conferences > ECBO > 2019 > NMCTA > 11073_18

Doppler Imaging of Intracellular Dynamics in Clinical Cancer Chemotherapy

David D. Nolte, John J. Turek, Daniela E. Matei MD, and Shadia Jalal MD

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Abstract

Biodynamic imaging of chemotherapy response in ex vivo patient biopsies measures changes of intracellular dynamics in response to applied therapeutics. The technique is based on near-IR low-coherence digital holography of Doppler-broadened light scattering from intracellular dynamics. Three clinical trials of this diagnostic biophotonic technology are nearing completion in esophageal cancer, epithelial ovarian cancer and breast cancer.

© 2019 SPIE/OSA

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