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Conferences > ECBO > 2011 > PSVI > 80890Q

Multi-spectral photoacoustic mapping of bacteriochlorins diffusing through the skin: exploring a new PAT contrast agent

Fábio A. Schaberle, Luís A. F. Reis, Gonçalo F. F. Sá, Carlos Serpa, Artur R. Abreu, Mariette M. Pereira, and Luis G. Arnaut

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Abstract

A skin depth map was built reconstructing photoacoustic signals at several wavelengths of visible and infrared light. The mapping technique was used to follow the diffusion through the skin of near-infrared absorbing dyes. Such dyes can be useful for photodynamic therapy (PDT) of skin lesions and are investigated as contrast agents for photoacoustic tomography (PAT), because they strongly absorb light at wavelengths where the skin is more transparent.

© 2011 OSA/SPIE

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