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High-resolution imaging of mouse anatomy with a multi-purpose optoacoustic tomography system

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Abstract

Optoacoustic imaging can noninvasively provide visualization of vasculature structures with optical contrast well below the skin surface. For meaningful biological investigations, high-resolution at mesoscopic penetration depths and therefore thorough adaption of the systematic arrangement to the object of interest is required. A suitable modular optoacoustic tomography system is presented here and its performance is demonstrated in three exemplary studies on imaging agar phantoms, mouse head vasculature and mouse tumor vasculature ex-vivo.

© 2011 OSA/SPIE

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