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Conferences > ECBO > 2011 > NMTB > 808808

Simultaneous imaging of haemoglobin oxygenation and blood flow with RGB reflectometry and LASCA during stroke in rats

A. Steimers, M. Gramer, M. Takagaki, R. Graf, and M. Kohl-Bareis

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Abstract

We demonstrate the simultaneous mapping of haemoglobin oxygenation and blood flow changes of human skin and the exposed cortex in rats by broad-band reflectometry and laser speckle contrast analysis (LASCA). A hard- and software set-up is realized with a high temporal resolution achieved by techniques of multi- and manycore computing. Spatial and temporal resolved changes of haemoglobin oxygenation and blood flow in rats are observed in response to middle cerebral artery occlusion and cortical spreading depression.

© 2011 OSA/SPIE

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