Which histological characteristics of basal cell carcinomas influence the quality of optical coherence tomography imaging?

M. Mogensen; L. Thrane; T.M Joergensen; B.M. Nürnberg; G.B.E. Jemec

doi:10.1364/ECBO.2009.7372_1U

Optical Coherence Tomography and Coherence Techniques IV
Proceedings of SPIE-OSA Biomedical Optics (Optica Publishing Group, 2009),
paper 7372_1U
•https://doi.org/10.1364/ECBO.2009.7372_1U

Which histological characteristics of basal cell carcinomas influence the quality of optical coherence tomography imaging?

M. Mogensen, L. Thrane, T.M Joergensen, B.M. Nürnberg, and G.B.E. Jemec

European Conference on Biomedical Optics 2009

Munich Germany
14–18 June 2009
ISBN: 9780819476487

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M. Mogensen, L. Thrane, T. M. Joergensen, B. M. Nürnberg, and G. B. E. Jemec, "Which histological characteristics of basal cell carcinomas influence the quality of optical coherence tomography imaging?," in Optical Coherence Tomography and Coherence Techniques IV, P. Anderson and B. Bouma, eds., Vol. 7372 of Proceedings of SPIE-OSA Biomedical Optics (Optica Publishing Group, 2009), paper 7372_1U.

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Abstract

We explore how histopathology parameters influence OCT imaging of basal cell carcinomas (BCC) and address whether such parameters correlate with the quality of the recorded OCT images. Our results indicate that inflammation impairs OCT imaging and that sun-damaged skin can sometimes provide more clear-cut images of skin cancer lesions using OCT imaging when compared to skin cancer surrounded by skin without sun-damage.

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