Abstract

An imaging system that records autofluorescence images calibrated by the cross-polarized reflection images from excitation was instrumented to evaluate the capabilities of a calibrated autofluorescence imaging method for detecting neoplastic lesions. Cervical tissue was selected as the living tissue material. It was found that neoplastic lesions can be differentiated from surrounding normal tissue based on the contrast in the calibrated autofluorescence signals, which from neoplastic lesions were generally lower than that from normal cervical tissue.

© 2003 SPIE