Label-Free Phenotyping of Human Cells with Multimodal Quantitative-Phase Digital Holographic Microscopy: Towards the Identification of New Cellular Biomarkers of Diseases

Erik Bélanger; Émile Rioux-Pellerin; Céline Larivière-Loiselle; Pierre Beausoleil; Sara Mattar; Chloé Martel; Marie-Ève Crochetière; Jean-Xavier Giroux; Pierre Marquet

doi:10.1364/DH.2020.HW4C.3

Imaging and Applied Optics Congress
OSA Technical Digest (Optica Publishing Group, 2020),
paper HW4C.3
•https://doi.org/10.1364/DH.2020.HW4C.3

Label-Free Phenotyping of Human Cells with Multimodal Quantitative-Phase Digital Holographic Microscopy: Towards the Identification of New Cellular Biomarkers of Diseases

Erik Bélanger, Émile Rioux-Pellerin, Céline Larivière-Loiselle, Pierre Beausoleil, Sara Mattar, Chloé Martel, Marie-Ève Crochetière, Jean-Xavier Giroux, and Pierre Marquet

Digital Holography and Three-Dimensional Imaging 2020

Washington, DC United States
22–26 June 2020
ISBN: 978-1-943580-77-4

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Digital Holographic Techniques for Bio-imaging III (HW4C)

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E. Bélanger, É. Rioux-Pellerin, C. Larivière-Loiselle, P. Beausoleil, S. Mattar, C. Martel, M. Crochetière, J. Giroux, and P. Marquet, "Label-Free Phenotyping of Human Cells with Multimodal Quantitative-Phase Digital Holographic Microscopy: Towards the Identification of New Cellular Biomarkers of Diseases," in Imaging and Applied Optics Congress, OSA Technical Digest (Optica Publishing Group, 2020), paper HW4C.3.

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Abstract

We demonstrate label-free cell phenotyping by measuring various biophysical parameters with a multimodal imaging system based on quantitative-phase digital holographic microscopy. Different developments allowing the monitoring, in various paradigms, of specific biophysical parameters are presented.

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