Robustly detecting imaging model mismatches and reconstruction artifacts in single-molecule localization microscopy

Hesam Mazidi; Tianben Ding; Arye Nehorai; Matthew D. Lew

doi:10.1364/COSI.2021.CTu4B.5

OSA Imaging and Applied Optics Congress 2021 (3D, COSI, DH, ISA, pcAOP)
OSA Technical Digest (Optica Publishing Group, 2021),
paper CTu4B.5
•https://doi.org/10.1364/COSI.2021.CTu4B.5

Robustly detecting imaging model mismatches and reconstruction artifacts in single-molecule localization microscopy

Hesam Mazidi, Tianben Ding, Arye Nehorai, and Matthew D. Lew

Computational Optical Sensing and Imaging 2021

Washington, DC United States
19–23 July 2021
ISBN: 978-1-943580-89-7

From the session
Computational Microscopy II (CTu4B)

Not Accessible

Your library or personal account may give you access

Get PDF
Email
Share
Get Citation
Copy Citation Text
H. Mazidi, T. Ding, A. Nehorai, and M. D. Lew, "Robustly detecting imaging model mismatches and reconstruction artifacts in single-molecule localization microscopy," in OSA Imaging and Applied Optics Congress 2021 (3D, COSI, DH, ISA, pcAOP), H. Hua, B. Javidi, M. Martinez-Corral, O. Matoba, A. Stern, S. Thibault, T. Alieva, J. Ke, F. Willomitzer, F. Okten, P. Silveira, P. Banerjee, E. Stoykova, D. Chu, J. Park, F. Imai, C. Joo, M. Digman, D. Gardner, S. Gladysz, D. LeMaster, S. Basu, and O. Korotkova, eds., OSA Technical Digest (Optica Publishing Group, 2021), paper CTu4B.5.

Export Citation
- BibTex
- Endnote (RIS)
- HTML
- Plain Text
Get Video
Citation alert
Save article

Abstract

We demonstrate Wasserstein-induced flux (WIF) for measuring localization stability in localization microscopy. Without knowing the ground truth structure being im- aged, WIF detects model mismatch within reconstruction algorithms and nanoscale imag- ing artifacts with high sensitivity.

PDF Article | Presentation Video

More Like This

Imaging chemical environments and amyloid architectures using single-molecule orientation-localization microscopy

Tianben Ding, Jin Lu, Tingting Wu, and Matthew D. Lew
ITu7A.6 Imaging Systems and Applications (IS) 2021

Snapshot multi-PSF 3D single-molecule localization microscopy using deep learning

Hayato Ikoma, Yifan Peng, Michael Broxton, and Gordon Wetzstein
CW3B.3 Computational Optical Sensing and Imaging (COSI) 2020

Simultaneous Multicolor Spectroscopic Single-molecule Localization Microscopy Image Reconstruction using Machine Learning

Sunil Kumar Gaire, Ethan Flowerday, Jane Frederick, Ruyi Gong, Leslie Ying, Hao F. Zhang, and Vadim Backman
IM4E.4 Imaging Systems and Applications (IS) 2023

Previous Article Next Article

Presentation Video

Presentation video access is available to:

Optica Publishing Group subscribers
Technical meeting attendees
Optica members who wish to use one of their free downloads. Please download the article first. After downloading, please refresh this page.

Contact your librarian or system administrator
or
Log in to access Optica Member Subscription or free downloads