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Assessing Airway Smooth Muscle Microstructure and Contractile Force in Vivo Using Birefringence Microscopy

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Abstract

Excessive contraction of airway smooth muscle (ASM) is responsible for the majority of the symptoms of asthma. We have developed a birefringence microscopy platform to volumetric assess ASM in patients and to quantify and predict ASM contractile force as a function of optical retardation.

© 2017 Optical Society of America

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