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Portable instrument for paper-based isothermal nucleic acid amplification tests

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Abstract

This paper demonstrates a paper-based nucleic acid amplification test with a portable instrument. The paper-based sensor provides the functions of reagent storage, sample transportation, and DNA amplification. The compact and low-cost fluorescence detector can quantify the amplicons in real-time. The results show that the sensor can detect multiple target genes with the concentration as low as 2 X 104 copies/gL.

© 2020 The Author(s)

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