The CAI Instrument: a Novel Optical Device for Sepsis Analysis for POCT applications

F. Baldini; A. Giannetti; C. Trono; L. Bolzoni; G. Porro

Proceedings of the International Quantum Electronics Conference and Conference on Lasers and Electro-Optics Pacific Rim 2011
(Optica Publishing Group, 2011),
paper C974

The CAI Instrument: a Novel Optical Device for Sepsis Analysis for POCT applications

F. Baldini, A. Giannetti, C. Trono, L. Bolzoni, and G. Porro

Conference on Lasers and Electro-Optics/Pacific Rim 2011

Sydney Australia
28 August–1 September 2011
ISBN: 978-0-9775657-7-1

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Session 7: Symposium 5 - Biomedical Applications (BA)

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F. Baldini, A. Giannetti, C. Trono, L. Bolzoni, and G. Porro, "The CAI Instrument: a Novel Optical Device for Sepsis Analysis for POCT applications," in Proceedings of the International Quantum Electronics Conference and Conference on Lasers and Electro-Optics Pacific Rim 2011, (Optica Publishing Group, 2011), paper C974.

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Abstract

In the last years, there has been a strong request of the physicians for point-of-care testing (POCT) instrumention. The present paper deals with the characterisation of a POCT optical instrument, the channel array interrogation (CAI) device, developed for the simultaneous detection of biomarkers for sepsis. The portable device was optimized for the determination of procalcitonin (PCT) and C-reactive protein (CRP), the main biomarkers for sepsis. Limit of detection equal to 1.3 g L⁻¹ and to 2 g L⁻¹ for CRP and PCT, respectively were achieved.

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