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Conferences > CLEO > 2009 > CTuCC > CTuCC6
  • Conference on Lasers and Electro-Optics/International Quantum Electronics Conference
  • OSA Technical Digest (CD) (Optica Publishing Group, 2009),
  • paper CTuCC6
  • •https://doi.org/10.1364/CLEO.2009.CTuCC6

Real-time, Label-free Protein Binding Detection with a One Dimensional Photonic Crystal Sensor

Yunbo Guo, Thommey P. Thomas, Jing Yong Ye, Andrzej Myc, James R. Baker, and Theodore B. Norris

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Abstract

A one-dimensional photonic crystal structure in a total-internal-reflection geometry has been developed for real-time, label-free specific protein binding detection. With the streptavidin-biotin system, an ultra low mass density detection limit 24 fg/mm2 was achieved.

© 2009 Optical Society of America

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