Abstract

Techniques of optical spectroscopy—fluorescence emission and Raman and elastic scattering—can be used to diagnose diseased tissue and extract biochemical and morphological information. Data can be obtained in real time during clinical procedures using optical fiber contact probes, needles, and endoscopic imaging techniques. Clinical results and their biological basis will be presented. Prospects for spectral imaging in two and three dimensions will be discussed.

© 2002 Optical Society of America