Optical Quantification of Cerebral Hemodynamics During Deep Hypothermic Cardiopulmonary Bypass with Selective Cerebral Perfusion

Tiffany S. Ko; Constantine D. Mavroudis; Wesley B. Baker; Timothy W. Boorady; Vincent C. Morano; Yuxi Lin; Jonah A. Padawer-Curry; Mahima Devarajan; Anna L. Roberts; Will P. Landis; Kristen N. Andersen; Alexander L. Schmidt; Javier Gentile; Richard W. Melchior; Arjun G. Yodh; J. William Gaynor; Todd J. Kilbaugh; Daniel J. Licht

doi:10.1364/BRAIN.2020.BTh4C.5

Biophotonics Congress: Biomedical Optics 2020 (Translational, Microscopy, OCT, OTS, BRAIN)
OSA Technical Digest (Optica Publishing Group, 2020),
paper BTh4C.5
•https://doi.org/10.1364/BRAIN.2020.BTh4C.5

Optical Quantification of Cerebral Hemodynamics During Deep Hypothermic Cardiopulmonary Bypass with Selective Cerebral Perfusion

Tiffany S. Ko, Constantine D. Mavroudis, Wesley B. Baker, Timothy W. Boorady, Vincent C. Morano, Yuxi Lin, Jonah A. Padawer-Curry, Mahima Devarajan, Anna L. Roberts, Will P. Landis, Kristen N. Andersen, Alexander L. Schmidt, Javier Gentile, Richard W. Melchior, Arjun G. Yodh, J. William Gaynor, Todd J. Kilbaugh, and Daniel J. Licht

Optics and the Brain 2020

Washington, DC United States
20–23 April 2020
ISBN: 978-1-943580-74-3

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NIRS Clinical Applications (BTh4C)

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T. S. Ko, C. D. Mavroudis, W. B. Baker, T. W. Boorady, V. C. Morano, Y. Lin, J. A. Padawer-Curry, M. Devarajan, A. L. Roberts, W. P. Landis, K. N. Andersen, A. L. Schmidt, J. Gentile, R. W. Melchior, A. G. Yodh, J. W. Gaynor, T. J. Kilbaugh, and D. J. Licht, "Optical Quantification of Cerebral Hemodynamics During Deep Hypothermic Cardiopulmonary Bypass with Selective Cerebral Perfusion," in Biophotonics Congress: Biomedical Optics 2020 (Translational, Microscopy, OCT, OTS, BRAIN), OSA Technical Digest (Optica Publishing Group, 2020), paper BTh4C.5.

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Abstract

Non-invasive, frequency-domain diffuse optical spectroscopy and diffuse correlation spectroscopy were combined to quantify cerebral oxygen metabolism in a neonatal swine model of deep hypothermic cardiopulmonary bypass, circulatory arrest, and selective cerebral perfusion.

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