Concurrent Electrophysiology and Optoacoustic Tomography Enable Visualization of Deep Thalamocortical Activity in an Acute Mouse Model of Focal Epilepsy

Sven Gottschalk; Thomas Felix Fehm; Thomas Felix Fehm; Xose Luis Deán-Ben; Vassiliy Tsytsarev; Daniel Razanksy; Daniel Razanksy

doi:10.1364/BRAIN.2017.BrW3B.6

Optics in the Life Sciences Congress
OSA Technical Digest (online) (Optica Publishing Group, 2017),
paper BrW3B.6
•https://doi.org/10.1364/BRAIN.2017.BrW3B.6

Concurrent Electrophysiology and Optoacoustic Tomography Enable Visualization of Deep Thalamocortical Activity in an Acute Mouse Model of Focal Epilepsy

Sven Gottschalk, Thomas Felix Fehm, Xose Luis Deán-Ben, Vassiliy Tsytsarev, and Daniel Razanksy

Optics and the Brain 2017

San Diego, California United States
2–5 April 2017
ISBN: 978-1-943580-25-5

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Optics and Brain Disease (BrW3B)

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S. Gottschalk, T. F. Fehm, X. L. Deán-Ben, V. Tsytsarev, and D. Razanksy, "Concurrent Electrophysiology and Optoacoustic Tomography Enable Visualization of Deep Thalamocortical Activity in an Acute Mouse Model of Focal Epilepsy," in Optics in the Life Sciences Congress, OSA Technical Digest (online) (Optica Publishing Group, 2017), paper BrW3B.6.

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Abstract

Thalamocortical activity in epilepsy was studied in mice using an optoacoustic functional neuroimaging framework correlating hemodynamic responses with concurrent EEG-readings, demonstrating noninvasive real-time visualization of deep epileptic foci.

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