Seeing molecular vibrations: optical imaging of small molecules for biomedicine

Wei Min

doi:10.1364/OMP.2015.JW2B.3

Optics in the Life Sciences
OSA Technical Digest (online) (Optica Publishing Group, 2015),
paper JW2B.3
•https://doi.org/10.1364/OMP.2015.JW2B.3

Seeing molecular vibrations: optical imaging of small molecules for biomedicine

Wei Min

Optics and the Brain 2015

Vancouver Canada
12–15 April 2015
ISBN: 978-1-55752-954-1

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Molecular Imaging and Optogenetics (JW2B)

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W. Min, "Seeing molecular vibrations: optical imaging of small molecules for biomedicine," in Optics in the Life Sciences, OSA Technical Digest (online) (Optica Publishing Group, 2015), paper JW2B.3.

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Abstract

We report a novel imaging platform, by coupling stimulated Raman scattering microscopy with small vibrational tags (including isotopes and alkynes), to probe dynamics of small biomolecules in living organisms with superb sensitivity, specificity and biocompatibility.

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