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Quantifying Tissue Hemodynamics by NIRS versus DOT: Global versus Focal Changes in Cerebral Hemodynamics

David A. Boas, Xuefeng Cheng, and Joseph B. Mandeville

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Abstract

NIRS is unable to accurately quantify absolute focal changes in oxy-and deoxy-hemoglobin as well as relative changes. This is due to differential wavelength sensitivity to the focal region not accounted by the NIRS theory.

© 2000 Optical Society of America

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