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Diffuse Optical Tomography for Breast Cancer Imaging: Optimal Clinical Design for Sensitivity and Image Accuracy

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Abstract

Diffuse optical tomography can be used to accurately reconstruct images of the human breast, and can provide functional information about hemoglobin concentration and oxygen saturation. This study examines the influences of source-detector geometry upon image recovery and explicitly evaluates the detectability of objects at varying contrasts, as well as the accuracy with which the optical properties of those objects can be determined. Results from a clinical prototype optical imager will be shown to illustrate typical image quality. Case examples highlight where improvements in image quality can be made.

© 2000 Optical Society of America

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