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Combined fluorescence and reflectance spectroscopy for pre-cancer detection: How many measurements do we need?

Urs Utzinger, Michele Follen, and Rebecca Richards-Kortum

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Abstract

Fluorescence and reflectance spectroscopy have the potential to reduce the costs of cervical cancer screening and detection. Algorithms based on three to four emission spectra yield performance comparable to colposcopy in expert hands. Moderate size clinical trials are necessary to stratify measurements by patient age and hormonal status.

© 2000 Optical Society of America

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