Quantification of functional motor cortex activity using time-resolved spatially localized NIR spectroscopy

Vasilis Ntziachristos; Vasilis Ntziachristos; XuHui Ma; Arjun Yodh; Britton Chance

doi:10.1364/BOSD.1998.BTuD1

Biomedical Optical Spectroscopy and Diagnostics / Therapeutic Laser Applications
OSA Trends in Optics and Photonics (Optica Publishing Group, 1998),
paper BTuD1
•https://doi.org/10.1364/BOSD.1998.BTuD1

Quantification of functional motor cortex activity using time-resolved spatially localized NIR spectroscopy

Vasilis Ntziachristos, XuHui Ma, Arjun Yodh, and Britton Chance

Biomedical Optical Spectroscopy and Diagnostics 1998

Orlando, Florida United States
ISBN: 1-55752-547-1

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MOnitoring of Brain Function and Tissue Oxygenation (BTuD)

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V. Ntziachristos, X. Ma, A. Yodh, and B. Chance, "Quantification of functional motor cortex activity using time-resolved spatially localized NIR spectroscopy," in Biomedical Optical Spectroscopy and Diagnostics / Therapeutic Laser Applications, E. Sevick-Muraca and J. Izatt, eds., Vol. 22 of OSA Trends in Optics and Photonics (Optica Publishing Group, 1998), paper BTuD1.

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Abstract

We report the use of a home-made multi-channel time-correlated photon counting instrument, to monitor and quantify absorption changes in the contra-lateral primary motor cortex area occurring due to motor stimulation with voluntary finger tapping. The stimulation protocol is designed using an intensity modulated NIR instrument and optimized to quantify the maximum blood volume changes during activation.

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