A handheld confocal microscope with MEMS-based flat-field scanning for fluorescence-guided surgery

Linpeng Wei; Chengbo Yin; Sanjeewa Abeytunge; Gary Peterson; Michael J. Mandella; Milind Rajadhyaksha; Nader Sanai; Jonathan T.C. Liu; Jonathan T.C. Liu

doi:10.1364/BODA.2019.DS2A.5

Biophotonics Congress: Optics in the Life Sciences Congress 2019 (BODA,BRAIN,NTM,OMA,OMP)
OSA Technical Digest (Optica Publishing Group, 2019),
paper DS2A.5
•https://doi.org/10.1364/BODA.2019.DS2A.5

A handheld confocal microscope with MEMS-based flat-field scanning for fluorescence-guided surgery

Linpeng Wei, Chengbo Yin, Sanjeewa Abeytunge, Gary Peterson, Michael J. Mandella, Milind Rajadhyaksha, Nader Sanai, and Jonathan T.C. Liu

Bio-Optics: Design and Application 2019

Tucson, Arizona United States
14–17 April 2019
ISBN: 978-1-943580-54-5

From the session
Clinical Applications II (DS2A)

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L. Wei, C. Yin, S. Abeytunge, G. Peterson, M. J. Mandella, M. Rajadhyaksha, N. Sanai, and J. T. C. Liu, "A handheld confocal microscope with MEMS-based flat-field scanning for fluorescence-guided surgery," in Biophotonics Congress: Optics in the Life Sciences Congress 2019 (BODA,BRAIN,NTM,OMA,OMP), OSA Technical Digest (Optica Publishing Group, 2019), paper DS2A.5.

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Abstract

We developed a handheld line-scanned dual-axis confocal microscope for real-time optical biopsy. The device utilizes a novel MEMS-based scanning mechanism for field-flattening, and provides high-speed (16 Hz) fluorescence imaging with sub-nuclear resolution in tissue.

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