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Two-Photon Intravital Imaging of a Mouse Brain In Vivo Using Easily Prepared Ruthenium-Poloxamer Nanoprobes

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Abstract

A hydrophobic, oxygen-sensitive ruthenium-complex dye is prepared in water through a simple surfactant micellization technique. Two-photon imaging of a mouse brain vasculature in vivo is demonstrated using the probe with excellent detail and contrast.

© 2015 Optical Society of America

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