Abstract

There is a pressing clinical need to provide image guidance during surgery. Currently, assessment of tissue that needs to be resected or avoided is performed subjectively leading to a large number of failures, patient morbidity and increased healthcare cost. Because near-infrared (NIR) light propagates deeply within living tissues and interacts with molecular constituents, it offers unparalleled capabilities for objectively identifying healthy and diseased tissue intraoperatively. In this presentation, we will review our efforts in image-guided surgery using diffuse NIR light. In particular, we will present our latest developments in imaging devices, acquisition and processing methods for real-time & wide-field endogenous molecular contrast imaging.

© 2015 Optical Society of America