Abstract

The effect of optical properties and probe geometry on sampling depth for diffuse reflectance spectroscopy (DRS) was investigated using computational and experimental techniques. A two-layer Monte Carlo model was used to determine sampling depth for a wide range of optical properties and source-detector separations (SDS), and these results were experimentally validated. The results show that sampling depth can be increased by increasing SDS; however, for highly absorbing media, increasing SDS will not lead to increased sampling depth. The proposed method can be used to aid in the design of DRS probes for specific applications where sampling depth is an important factor.

© 2014 Optical Society of America