Macromolecular Crowding as a Regulator of Transcription

Igal Szleifer

doi:10.1364/BIOMED.2014.BM4A.7

Biomedical Optics 2014
OSA Technical Digest (online) (Optica Publishing Group, 2014),
paper BM4A.7
•https://doi.org/10.1364/BIOMED.2014.BM4A.7

Macromolecular Crowding as a Regulator of Transcription

Igal Szleifer

Biomedical Optics 2014

Miami, Florida United States
26–30 April 2014
ISBN: 978-1-55752-997-8

From the session
Biological Principles of Optical Diagnostic and Therapeutic Technologies (BM4A)

Open Access

Get PDF
Email
Share
Get Citation
Copy Citation Text
I. Szleifer, "Macromolecular Crowding as a Regulator of Transcription," in Biomedical Optics 2014, OSA Technical Digest (online) (Optica Publishing Group, 2014), paper BM4A.7.

Export Citation
- BibTex
- Endnote (RIS)
- HTML
- Plain Text
Get Video
Citation alert
Save article

Abstract

Inspired by PWS experiments showing cell nanostructural changes in early carcinogenesis, we developed models to study changes in transcription due to macromolecular crowding. We find that crowding can lead to nonmonotonic regulation of transcription

PDF Article | Presentation Video

More Like This

The Role of Nuclear Nano-Environment on DNA Dehybridization

Luay Matthew Almassalha, Lusik Cherkezyan, Greg Putzel, Vadim Backman, and Igal Szleifer
BT3A.39 Biomedical Optics (BIOMED) 2014

Imaging Gene Transcription

Christopher J. Fecko
LSThD1 Laser Science (LS) 2009

Studying σ54-dependent transcription at the single-molecule level using alternating-laser excitation (ALEX) spectroscopy

M. Heilemann, K. Lymperopoulos, S. R. Wigneshweraraj, M. Buck, and A. N. Kapanidis
6633_92 European Conference on Biomedical Optics (ECBO) 2007

Previous Article Next Article

Presentation Video