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Photodynamic Molecular Beacons: An Image–Guided Therapeutic Approach for Vertebral Metastases

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Abstract

We demonstrate the metastatic-specific activation of photodynamic molecular beacons by matrix metalloproteinases as a useful image-guidance tool with an unprecedented level of PDT selectivity for the therapeutic management of breast cancer spinal metastases.

© 2012 Optical Society of America

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