Abstract
We present a fiber-optic scanning second harmonic generation (SHG) endomicroscopy system that can detect the morphological changes in cervical collagen fiber during gestation with sub-micrometer resolution. Our preliminary results suggest a promising role of the SHG endomicroscopy technology for assessing abnormal remodeling of cervical collagen fiber associated with preterm birth.
© 2012 Optical Society of America
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