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Detection of decreased cerebral blood volume and oxygen saturation in folate deficient rats using non-invasive near-infrared spectroscopy

Bertan Hallacoglu, Angelo Sassaroli, Irwin H. Rosenberg, Sergio Fantini, and Aron M. Troen

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Abstract

We report non-invasive, absolute measurements of cerebral hemodynamics with frequency-domain, near infrared spectroscopy on a rat model of vascular cognitive impairment. Folate deficiency was found to induce measurable hemodynamic changes.

© 2010 Optical Society of America

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