Abstract
We employed non-invasive near-infrared (NIR) imaging to assess the lymphatic structure and function in normal human subjects and subjects diagnosed with unilateral lymphedema (LE). Imaging was performed following microdose, intradermal administrations of indocyanine green (ICG) in arms or legs. Half of the subjects received manual lymph drainage (MLD) treatment. Apparent lymph velocities and periods between lymphatic propulsion events were calculated from images. Noteworthy difference in lymphatic structure between normal and LE subjects was seen. The lymphatic function was significantly improved after MLD.
© 2010 Optical Society of America
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