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Conferences > BIOMED > 2010 > BTuD > BTuD33

Using Fluorescence Lifetime Imaging Microscopy to Monitor Photofrin Uptake, Re-distribution, and Intracellular Microenvironment

Shu-Chi Yeh, Tony J. Collins, Regina W. Leung, Kevin R. Diamond, and Qiyin Fang

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Abstract

Real-time dosimetry is important to photodynamic therapy treatments. In a cellular microscopy study, we measured the fluorescence lifetime changes of Photofrin® when it bonds to specific intracellular components at specific stages of the cellular uptake.

© 2010 Optical Society of America

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