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Screening Small Molecule Compounds for Protein Ligands with Label-Free, Optically Detected Microarrays

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Abstract

Using a high-throughput label-free optical scanner we measured endpoints and binding kinetics of human vascular endothelial growth factor (VEGF) protein against 8,000 small molecule compounds (in microarray format) from NCI Developmental Therapeutics Program.

© 2010 Optical Society of America

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