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Breeding and Building Molecules to Spy on Cells and Tumors

Open Access Open Access

Abstract

New flavoproteins photogenerate singlet oxygen, enabling genetically encoded correlative light and electron microscopy. Synthetic peptides provide an amplifying mechanism for targeting fluorophores, MRI contrast agents, and drugs to sites of protease activity (e.g. tumors) in vivo.

© 2010 Optical Society of America


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