Abstract

In this paper, we present highly sensitive imaging, with high resolution, of directional blood perfusion within both retinal and choroid, achieved by optical micro-angiography (OMAG) technology. An OMAG system operating at 840nm was used in the experiments. To provide blood vessel images within a larger field of view, we carried out the imaging of ocular blood perfusion by reconstructing sequentially registered multiple OMAG projection maps of small areas (~1mm×1mm). Algorithms were developed to minimize/remove the motion artifacts induced by the subject involuntary movements. The imaging time for a small sub-area (1×1 mm²) was ~3.7 sec, and ~2.5 min for a larger field of view (3×3 mm²). Finally, we present functional images of microcirculation in different depth regions of retina and choroid, which results show superior performance of OMAG to image ocular blood perfusion with high resolution and high sensitivity.

© 2010 Optical Society of America