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Conferences > BIOMED > 2010 > BSuD > BSuD81

Laser-induced Breakdown (LIB) of Optically Trapped Nanoparticles for Gene Transfection

Yoshihiko Arita, Maria Leilani Torres-Mapa, Woei Ming Lee, Tomáš Čižmár, Frank J. Gunn-Moore, and Kishan Dholakia

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Abstract

A novel approach to gene transfection is demonstrated. It uses laser-induced breakdown of an optically trapped single nanoparticle to achieve a high transfection efficiency in a quasi-targeted manner, without cell lysis, using a nanosecond laser.

© 2010 Optical Society of America

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