Quantitative Cerebral Blood Flow and Angiography with Optical Coherence Tomography

Vivek J. Srinivasan; Dmitriy N. Atochin; James Y. Jiang; Harsha Radhakrishnan; Mohammed A. Yaseen; Svetlana Ruvinskaya; Weicheng Wu; Scott Barry; Alex E. Cable; Paul L. Huang; David A. Boas

doi:10.1364/BIOMED.2010.BSuD56

Biomedical Optics and 3-D Imaging
OSA Technical Digest (CD) (Optica Publishing Group, 2010),
paper BSuD56
•https://doi.org/10.1364/BIOMED.2010.BSuD56

Quantitative Cerebral Blood Flow and Angiography with Optical Coherence Tomography

Vivek J. Srinivasan, Dmitriy N. Atochin, James Y. Jiang, Harsha Radhakrishnan, Mohammed A. Yaseen, Svetlana Ruvinskaya, Weicheng Wu, Scott Barry, Alex E. Cable, Paul L. Huang, and David A. Boas

Biomedical Optics 2010

Miami, Florida United States
11–14 April 2010
ISBN: 978-1-55752-887-2

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V. J. Srinivasan, D. N. Atochin, J. Y. Jiang, H. Radhakrishnan, M. A. Yaseen, S. Ruvinskaya, W. Wu, S. Barry, A. E. Cable, P. L. Huang, and D. A. Boas, "Quantitative Cerebral Blood Flow and Angiography with Optical Coherence Tomography," in Biomedical Optics and 3-D Imaging, OSA Technical Digest (CD) (Optica Publishing Group, 2010), paper BSuD56.

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Abstract

We perform regional cerebral blood flow measurements using Doppler OCT in the rat cortex and validate our results with hydrogen clearance. 3D angiography of cortical microvasculature is demonstrated, enabling rapid assessment of perfusion and tone.

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