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In vivo three-dimensional Fourier domain optical coherence tomography of subpleural alveoli combined with intra vital microscopy in the mouse model

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Abstract

Simultaneous Fourier domain optical coherence tomography and dark-field intravital video microscopy were used for in-vivo imaging of alveolar dynamics in the ventilated mouse. Quantification of the images revealed an alveolar expansion with increased end-inspiratory-pressure.

© 2008 Optical Society of America

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