Correlation between Optical Coherence Tomography (OCT) and Optical Intrinsic Signal Imaging (OISI) during Functional Brain Activation

Y. Chen; A.D. Aguirre; A.D. Aguirre; L. Ruvinskaya; A. Devor; D.A. Boas; D.A. Boas; J.G. Fujimoto

doi:10.1364/BIOMED.2008.BWC7

Biomedical Optics
OSA Technical Digest (CD) (Optica Publishing Group, 2008),
paper BWC7
•https://doi.org/10.1364/BIOMED.2008.BWC7

Correlation between Optical Coherence Tomography (OCT) and Optical Intrinsic Signal Imaging (OISI) during Functional Brain Activation

Y. Chen, A.D. Aguirre, L. Ruvinskaya, A. Devor, D.A. Boas, and J.G. Fujimoto

Biomedical Optics 2008

St. Petersburg, Florida United States
16–19 March 2008
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Techniques for Functional Neural Imaging (BWC)

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Y. Chen, A. D. Aguirre, L. Ruvinskaya, A. Devor, D. A. Boas, and J. G. Fujimoto, "Correlation between Optical Coherence Tomography (OCT) and Optical Intrinsic Signal Imaging (OISI) during Functional Brain Activation," in Biomedical Optics, OSA Technical Digest (CD) (Optica Publishing Group, 2008), paper BWC7.

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Abstract

Simultaneous OCT and OISI were performed on rat somatosensory cortex during forepaw stimulation. The depth-integrated OCT signal correlates well with OISI signal, while OCT resolves layer-specific dynamics in functional activation patterns indicating retrograde vessel dilation.

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