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Longitudinal Monitoring of 4T1-Tumor Physiology in vivo with Doxorubicin Treatment via Diffuse Optical Spectroscopy

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Abstract

A diffuse optical spectrometer was used to monitor 4T1 breast carcinoma tumors implanted in mice. Animals treated with doxorubicin showed relative increased oxygen saturation and decreased blood volume vs. controls, over a 10 day period.

© 2008 Optical Society of America

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