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Conferences > BIO > 2006 > TuC > TuC1

In-vivo Characterization of Her-2/neu carcinogenesis in Mice Using Fluorescence Molecular Tomography

Helen A. Shih, Stephen D. Windsor, Ralph Weissleder, and Vasilis Ntziachristos

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Abstract

We reconstruct different bio-markers in Her-2/neu mice using Fluorescence Molecular Tomography (FMT) and appropriate fluorescent probe strategies. Protease up-regulation can serve as a generic detection marker whereas more specific antibody based imaging can be employed for higher specificity and more sensitive detection.

© 2006 Optical Society of America

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